[SOLUTION] Windows Update Error 80072EFE on Vista

I was working on a Windows Vista laptop that was infected and all the user files were hidden. This is my third computer with similar symptoms this week… After running MalwareBytes’ Antimalware, some things just didn’t “feel” right and Windows Update wouldn’t work, with this error: Error 80072EFE.

After reading some, I found this post, which had the solution: run Kaspersky’s TDSSKiller. It found a boot sector virus; I chose to Restore the boot sector (which can be risky). It did the trick!